EBI Personnel Directory Tabakh, Hannah
Concentrations of biofuel required for an industrial process at a relevant scale in microorganisms have not yet been demonstrated, because the fuels are often toxic to the host organism. Fuels are also difficult to cheaply remove from the cell. This project is introducing a small-molecule secretion "pump" engineered to efflux the fuels of interest at high yield. The insights the team gains can be applied to develop pumps and transporters that secrete other small molecules of interest, such as inhibitors from hydrolysate or toxic metabolic side products.