EBI Personnel Directory Chu, Jhih-Wei


Biomass Depolymerization

Jhih-Wei Chu

jwchu@berkeley.edu

 

 

Project(s)

Molecular Mechanisms of the Enzymatic Decomposition of Cellulose Microfibrils

This project is developing mechanistic knowledge of elementary steps in the enzymatic decomposition of cellulosic materials. The team is modeling and simulating, in silico, the structural deformation of a cellulose microfibril by mechanical and thermophysical means; the cleavage of β-1,4-glycosidic bonds on the surfaces of a microfibril by cellulases; and the detachment of broken glucose chains from the microfibril into solution. Their effort will be joined with other UC Berkeley researchers who will employ complementary computational methodologies and stimulation strategies in analyzing the effects of ionic liquids (IL) on cellulosic materials.